Rejuran Polynucleotide Skin Treatment in London
Rejuran is an advanced regenerative polynucleotide treatment that improves skin quality, elasticity, hydration and overall skin health. It uses polynucleotides (PN) derived from purified salmon DNA to stimulate the skin’s natural repair mechanisms, promoting collagen production, tissue regeneration and improved cellular function.
Because Rejuran repairs skin from within rather than adding volume, it is a skin-quality treatment rather than a contouring filler, and is often chosen by patients seeking healthier, stronger and more youthful-looking skin.
It sits within our polynucleotide treatments and is delivered at our Harley Street clinic in London, as part of a medically led approach to skin rejuvenation, with plans tailored to your skin condition, concerns and long-term goals.
What Is Rejuran?
The Science Behind Polynucleotides
Rejuran contains polynucleotides (PN), chains derived from purified salmon DNA, used in regenerative aesthetic treatments to support skin repair, hydration, elasticity and overall skin quality.
Rather than filling or reshaping the face, Rejuran works by supporting the skin’s own repair mechanisms, promoting collagen production and tissue regeneration. This makes it suitable for patients looking to improve skin texture, fine lines, crepiness, dullness or signs of skin fatigue.
TREATMENT TIME
30 - 45 mins
PAIN LEVEL
2/5
DOWNTIME
minimal
SESSIONS NEEDED
a course of 3, 4 weeks apart
MAINTENANCE
every 6-12 months
PRICE
POA
What Rejuran Can Help With
Fine lines and crepey skin
Enlarged pores
Acne scarring
Redness
Dullness and uneven skin tone
Loss of firmness, elasticity and hydration
Areas Rejuran Can Treat
Rejuran can be used on the face, neck, decolletage and around the eyes, and is often combined with other aesthetic treatments to enhance overall results. Suitability for each area is assessed at consultation.
BENEFITS OF REJURAN
Improves Skin Quality
Rejuran helps support smoother, healthier-looking skin by targeting skin quality rather than facial volume.
Supports Skin Repair
Polynucleotides derived from purified salmon DNA are used to support the skin’s natural repair processes, making Rejuran suitable for skin that feels tired, fragile or compromised.
Helps Improve Texture and Elasticity
Treatment may help improve the appearance of fine lines, crepey skin, enlarged pores, acne scarring and redness, uneven texture and loss of elasticity over time.
Natural-Looking Rejuvenation
Because Rejuran does not add structural volume, results are subtle and focused on skin health.
Suitable for Delicate Areas
Rejuran may be considered for delicate areas such as the under-eye region, as well as the face, neck and decolletage, depending on individual suitability.
Rejuran vs Fillers and Skin Boosters
Rejuran is not a dermal filler. Unlike fillers, which add volume or reshape features, Rejuran repairs skin from within to improve its quality. It is sometimes grouped with skin boosters and treatments such as Profhilo because they all aim to improve hydration and skin quality, though they use different active ingredients. Our team can explain how Rejuran compares during your consultation.
Your Rejuran Treatment Journey
Your Rejuran journey begins with a skin consultation. We assess your skin quality, hydration, sensitivity, texture, laxity and signs of ageing before advising whether Rejuran is the right treatment for you.
The treatment involves a series of small injections placed into the skin. Mild redness, swelling or small bumps can appear after treatment, but these usually settle within 24 to 72 hours.
For best results, Rejuran is recommended as a course of 3 treatments spaced 4 weeks apart, followed by maintenance every 6 to 12 months, depending on your skin response and goals. Improvements typically begin after 2 to 4 weeks, with optimal results following completion of the course.
What to Expect During Treatment
Our medical team will assess whether Rejuran is suitable for you, explain the expected treatment course and advise how it may be combined with other treatments such as skin boosters, Profhilo, laser or energy-based treatments if appropriate.
PREPARATION AND AFTERCARE
Preparation
At Harley Street Injectables, everything starts with a detailed consultation to understand your skin concerns and to check that a polynucleotide-based regenerative treatment is the right fit for your skin, goals and lifestyle. From there, a personalised plan is put together, typically a course of 3 treatments spaced 4 weeks apart, to support visible improvements in skin quality, texture and resilience, followed by maintenance every 6 to 12 months.
Aftercare
Mild redness, swelling, tenderness and small injection bumps are common immediately after treatment and typically settle within 24 to 72 hours. Occasional bruising may occur. We recommend avoiding strenuous exercise, excessive heat and sun exposure for 24 to 48 hours following treatment. Your practitioner will give you tailored aftercare advice.
FAQs
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Rejuran is an injectable polynucleotide treatment designed to support skin repair, improve skin quality and encourage healthier-looking skin.
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No. Rejuran is not used to add volume or reshape facial features. It is a regenerative skin treatment focused on improving skin quality.
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Rejuran may help improve the appearance of fine lines, dullness, uneven texture, crepiness and reduced skin resilience.
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Rejuran may be suitable for the under-eye area in some patients, but this depends on anatomy, skin thickness and the cause of the concern.
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A course of treatments is usually recommended. The exact number of sessions will depend on your skin condition and treatment goals.
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There may be redness, small bumps, swelling or bruising after treatment. These effects usually settle, but downtime varies between patients.
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Results develop gradually as skin quality improves. Your practitioner will discuss a realistic timeline during consultation.
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Item dePolynucleotides (PN) are chains derived from purified salmon DNA, used in regenerative aesthetic treatments to support skin repair, collagen production and hydration, improving overall skin quality over a course of sessions.scription
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Yes. Rejuran uses polynucleotides derived from purified salmon DNA, which is why it is sometimes called a salmon DNA skin treatment.
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Rejuran is priced on application, as the right course depends on your skin and goals. You will receive clear pricing following your consultation.
WHY CHOOSE
HARLEY STREET INJECTABLES?
EXPERTISE
Our London Doctors and Nurses perform over 5000+ Injectable treatments annually.
COMPASSIONATE CARE
Our team provides compassionate care and support throughout your treatment journey.
SAFETY
As a CQC registered medical clinic, we adhere to the highest standards of safety and quality assurance. Your health and safety are our top priorities.
BOOK A Consultation
If you are interested in Rejuran, book a consultation with Harley Street Injectables.
Our medical team will assess your skin and create a tailored plan to help improve skin quality, texture and resilience.